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April 25, 2008
News Headlines
Estrogen More
Suppressed with Letrozole than Anastrozole
Cisplatin Not Effective in Anal Cancer: Study
Melanoma on Scalp,
Neck Most Deadly
Mammography
Benefits May Have No Age Limit
Bevacizumab Can Be
Added to Chemoradiotherapy for Head and Neck
Multipolar
Radiofrequency Ablation Yields High Liver Cancer Survival Rates
Better Use of
Palliative Care Eases Suffering of Children with Cancer
Bias Threatens Validity of Observational Studies of Cancer Treatment
Cancerpage news is updated daily, Monday
through Friday, and on the weekends as
warranted. Nineteen new
articles have been added to cancerpage news since the last newsletter.
To see ALL the latest stories, go to the
cancerpage.com search page and click on Submit (but
leave search field black.)
Celebrating DNA - Cautioning Against Misuse
A bill prohibiting employers and insurance companies from discriminating against
people because DNA testing shows increased risk of disease passed the U.S.
Senate 95-0 Thursday. "Up until now, our laws have not kept pace with emerging technology,"
Maine Republican Senator Olympia Snowe
told Bloomberg News. The bill is slightly different from the measure that
cleared the U.S. House last year but the changes are expected to be accepted by
the House and then on the way to the President for signature. Some genetic
tests, such as the test for BRCA1 and 2 mutations, have been validated as
predictive of increased risk of developing certain cancers. There are even
stronger associations shown between certain genetic mutations and other diseases
such as Huntington's disease, a degenerative brain disorder.
At the same time, concerns are being raised that the desire for commerce and
profits is getting ahead of the science. Writing earlier this month in Science
magazine, researchers at the Genetics and Public Policy Center at Johns Hopkins University
warn that "Misleading marketing claims are particularly troubling when tests are
sold directly to consumers (DTC), because there is no health-care provider to serve as a
"gatekeeper" to prevent inappropriate test ordering or misinterpretation of test results." For instance,
genetic tests are being marketed by 15 companies that claim to predict
side effects and best dosing for commonly
prescribed SSRI antidepressants even though a CDC study showed no convincing evidence
that the tests results improved patient outcomes.
Read more
here.
Cancer Cure
Fraud
A former resident of Broward County, Florida, who hawked phony cancer cures over
the internet from the Netherlands has been sentenced to 17 1/2 years in jail.
Arthur VanMoor was found guilty of conspiracy to commit mail fraud, wire fraud,
misbranding of drugs and the
introduction of unapproved new drugs into interstate commerce in January, sentenced earlier this
month, and ordered to pay $1,900. A hearing to establish how much money he owes
in restitution to victims of his fraud will be held within the next three
months.
Read the FBI release on the case
here and a short story in the Sun Sentinel
here.
To Bring Home the Gold
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Brain tumor won't stop this Olympic hopeful.
Marin Morrison is a 17-year-old swimmer from Washington state. Seattle
Times columnist Steve Kelly tells her story this week. He reports
that two years ago the Make-A-Wish Foundation hoped she would live long enough
for them to send Morrison to the Beijing Olympics as a spectator. Instead
she's going as a competitor on the US Paralympic Swim Team and believes
she can medal in her sport. Read her inspiring story
here.
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Olympic Follow-Up
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American marathoner Emily LeVan (who we told you
about here last week) did not make the U.S. Olympic
Women's Marathon team at the Olympic
trials last weekend
but she called her run "probably the sweetest victory of any race I have ever run."
She writes: " I was completely overwhelmed by the outpouring of support for me, Maddie
[her infant daughter diagnosed with leukemia], and Two Trials, as I ran along the loop course.
" You can read about her run at her web site
here. |
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Drug
Approved to Reduce Opioid-Induced Constipation
The FDA approved a new drug this week, methylnaltrexone bromide, to
restore bowel function to patients with late-stage disease getting opioids on a continuous basis to relieve pain.
Constipation can be a life-threatening complication of long-term opioid pain control. Both natural and synthetic
opioids (drugs such as morphine, codeine, fentanyl, and oxycodone) relax the muscles of the
intestinal tract.
The new drug blocks the opioid from the muscle cells without interfering with the painkilling function.
Read the FDA release about the approval
here.
You can find out more about the drug
here.
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